I am once again stunned at the insistence that Star Trek has to be allegorically relevant, but if it must, I'd prefer it take on more scientific/ethical issues, like a justification for banning genetic enhancement, or how a society with FTL, molecular replication, and teleportation has managed to sidestep a technological singularity.
In short, Trek needs to catch up with the rest of science fiction.
It would be much more compelling and cohesive than a series of Shakespeare quote-riddled morality plays about slavery/holographic rights/drug addiction/whatever. The idea of a biological race eschewing a singularity yet still roaming out amongst the older/more powerful/scarier races could have a nice Brin/Uplift tone to it. Babylon 5 touched on this, but didn't really pursue it to the extent it could have.
With the exception of Farscape, Military SF seems to be the default setting for TV SF. Even Firefly delved into several times. The only other recent American shows I can think of which really avoided it were Earth II (which replaced it with political conspiracy) and Earth: Final Conflict, both of which were horrible. Compare this to the whole of written SF, where military stories make up a much smaller portion.
Also: the idea of bringing the Enterprise "back to the glory days" sounds a bit to much like Andromeda to me. I'm uncomfortable with stories where the good guys are trying to instigate a big step backwards.
Forgive me for not posting yesterday. I had a lot of things going on, chief among them was finishing the corrections to Solstice Chronicles, which is now available for $7.95 over at Lulu.com. There is still plenty of time to order one before the Holidays decend upon us. I intend to annoy you all with frequent reminders of this.